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Khloe Kardashian © NBC

IMPRESSIVE TRANSFORMATIONS

Celebrities talking about Ozempic: Khloe Kardashian, Ice Spice, Kelly Clarkson, and more

Hollywood’s spotlight turns to dramatic weight-loss transformations among celebrities


Daniel Neira
Daniel Neira - Los Angeles
Senior WriterLos Angeles
JANUARY 1, 2025 12:10 PM EST

There is no denying that Ozempic and other semaglutide drugs have been a topic of discussion this year. Weight-loss transformations have also been present in Hollywood, with many online users wondering about the impact of Ozempic in the lives of celebrities and A-List stars.

Some celebrities choose to keep their personal lives, including their health and fitness journeys, private. However, others openly discuss these topics, either confirming or denying rumors about their body changes. These public comments often lead to big conversations among fans and the media, fueling ongoing curiosity. Whether they are open or secretive about these issues shows how much public attention celebrities get in today’s digital world.

Discover their thoughts on using Ozempic and how it impacts their daily and work lives

Kelly Clarkson© Kevin Kane

Kelly Clarkson

"Mine is a different [drug] than people assume, but I ended up having to do that too because my bloodwork got so bad," she said on her show. "My doctor chased me for two years, and I was like, 'No, I'm afraid of it. I already have thyroid problems.' Everybody thinks it's Ozempic, but it's not. It's something else."

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Whoopi Goldberg

"First of all, it's all the weight I've lost. I've lost almost two people. I am doing that wonderful shot that works for folks who need some help, and it's been really good for me," she said on The Kelly Clarkson show. 

Bella Thorne at Sundance 2023© Corey Nickols

Bella Thorne

"So, I haven't been feeling good about my body for a while and especially with everybody on Ozempic — it's, like, setting all these crazy beauty standards that nobody can keep up with unless you're on Ozempic ... I'm finally feeling good, so Ozempic, you can [middle finger raised] off," Bella said on Instagram Stories.

Ashley Benson© River Callaway

Ashley Benson

“I know a lot of people take Ozempic and that's totally fine. To each their own. But don't discredit people who also work very hard to get their body back like I've done with mine ... Getting back to work forced me to focus on my health and working out and I wanted to feel confident and good about myself," the new mom said.

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Ice Spice

"I wish y'all never learned the word Ozempic. That's one thing I wish. Oh my God, like, what even is Ozempic? What the f--- is that? Genuinely, what is that?" She said on X. "It's called the gym. It's called eating healthy. It's called being on tour. Like, what the hell? Maybe if I was sitting home all day, it would be easier to stay big."

Khloe Kardashian © NBC

Khloe Kardashian

"Let's not discredit my years of working out. I get up 5 days a week at 6am to train. Please stop with your assumptions. I guess new year still means mean people," she said on Instagram.

Tori Spelling © Jeff Kravitz

Tori Spelling

“I did Mounjaro and everyone admits it now. It’s a different time so I don’t feel shamed saying that," she said on her podcast 'misSPELLING.' “I did whatever anyone told me to do that was safe and it just wasn’t working. The weight wouldn’t come off.”

Oprah© Getty Images

Oprah

"I now use [an unnamed weight loss drug] as I feel I need it, as a tool to manage not yo-yoing. The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for," Oprah revealed to People.


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Kelly Osbourne

"I think it's amazing. There are a million ways to lose weight, why not do it through something that's isn't as boring as working out? The people who hate on it the most are the people who are secretly doing it or pissed off that they can't afford it. Unfortunately, right now it's something that is very expensive but it eventually won't be because it actually works," she said to E! Online.

Kathy Bates© Gregg DeGuire

Kathy Bates

“There’s been a lot of talk that I just was able to do this because of Ozempic, but I have to impress upon people out there that this was hard work for me, especially during the pandemic. It’s very hard to say you’ve had enough," she said to People, explaining that she lost 80lbs before using Ozempic.

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